Code
NTG-ALLX-02CX
Profile
Active-Compendium
81450
88374x2
88374x2
Clinical
Oncology,Pathology
<p>Bone Marrow Aspirate: 2-3 mL in EDTA tube.<br/>
Peripheral Blood: 3-5 mL in EDTA tube.<br/>
H&E slide (required) plus paraffin block.<br/>
Cut Slides: H&E slide (required) plus 10-14 unstained slides cut at 5+ microns.<br/>
Note on FFPE: Paraffin block is preferred. Do not use zinc fixatives. If submitting slides, please use positively-charged slides and 10% NBF fixative. Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.<br/>
Do not use mercury fixatives (B5). Highly acidic or prolonged decalcification processes will not yield sufficient nucleic acid to accurately perform molecular studies.<br/>
Note: Test is TNA-based. Please select Extract & Hold - TNA If specimen hold service is desired.<br/>
Note for FFPE: Not validated specimen type for FISH testing.</p>
Peripheral Blood: 3-5 mL in EDTA tube.<br/>
H&E slide (required) plus paraffin block.<br/>
Cut Slides: H&E slide (required) plus 10-14 unstained slides cut at 5+ microns.<br/>
Note on FFPE: Paraffin block is preferred. Do not use zinc fixatives. If submitting slides, please use positively-charged slides and 10% NBF fixative. Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.<br/>
Do not use mercury fixatives (B5). Highly acidic or prolonged decalcification processes will not yield sufficient nucleic acid to accurately perform molecular studies.<br/>
Note: Test is TNA-based. Please select Extract & Hold - TNA If specimen hold service is desired.<br/>
Note for FFPE: Not validated specimen type for FISH testing.</p>
Flag Active
True
Orderable Test Description
<p>The NeoTYPE ALL Profile analyzes 50 genes to detect DNA and RNA alterations through a combination of next-generation sequencing (NGS) and FISH. Test reports include summary interpretation of all results to help guide treatment decisions.<br><br>
FISH components may be ordered as "Tech-Only" by pathology clients who wish to perform the professional component.</p>
FISH components may be ordered as "Tech-Only" by pathology clients who wish to perform the professional component.</p>
Orderable Turn Around Time
14 Days
Orderable Biomarkers
NY Approved
False
Orderable Biomarkers JSON
{"DNA Sequencing": {"SNVs + Indels": ["ABL1", "ABL2", "CDKN2A", "CRLF2", "CSF1R", "EPOR", "FBXW7", "FGFR2", "FGFR3", "FLT3", "IDH1", "IDH2", "IKZF1", "IL7R", "JAK1", "JAK2", "JAK3", "KRAS", "NOTCH1", "NRAS", "NTRK1", "NTRK2", "NTRK3", "PAX5", "PDGFRA", "PDGFRB", "PHF6", "SH2B3", "TP53"], "CNVs": ["CDKN2A", "IKZF1", "TP53"]}, "RNA Sequencing": {"Fusions": ["ABL1", "ABL2", "BCL11B", "BCR", "CRLF2", "CSF1R", "EPOR", "ETV6", "FGFR1", "FLT3", "IKZF1", "JAK2", "KMT2A", "MEF2D", "MLLT10", "MYB", "NTRK1", "NTRK2", "NTRK3", "NUP214", "NUP98", "PAX5", "PBX1", "PDGFRA", "PDGFRB", "PTK2B", "RUNX1", "STIL", "TAL1", "TCF3", "TLX1", "TLX3", "TYK2", "ZNF384"]}, "Fluorescence In Situ Hybridization (FISH)": {"CNVs": ["CRLF2", "EPOR"]}}
Keywords string
Acute lymphoblastic leukemia, Myeloid disorders, heme cancers, hematologic malignancies NeoTYPE® ALL Profile
Title URL
neotype-all-profile
TAT Details
NGS: 14 Days
FISH: 5 Days
Storage and transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. Ship same day as drawn whenever possible. Please select Extract & Hold - TNA if specimen hold service is desired.