Code
MOG-RAFX-03BZ
Profile
Active-Compendium
Molecular: Client-bill only, if ordered concurrently with Neo Comprehensive - Myeloid Disorders, or one of the NeoTYPE Heme Profiles.
Clinical
Oncology,Pathology
<p>Bone Marrow Aspirate: 2-3 mL in sodium heparin tube. EDTA is acceptable.<b>
Peripheral Blood: 5 mL in sodium heparin tube. EDTA is acceptable.<b>
Fluids: Mix in equal parts with RPMI (specimen volume to RPMI ratio of 1:1).</p>
Peripheral Blood: 5 mL in sodium heparin tube. EDTA is acceptable.<b>
Fluids: Mix in equal parts with RPMI (specimen volume to RPMI ratio of 1:1).</p>
Flag Active
True
Orderable Test Description
The Rapid AML Therapeutic Panel was designed to assess key biomarkers associated with acute myeloid leukemia (AML) through a combination of next-generation sequencing (NGS) and FISH. Test reports include a summary of all results to help guide treatment decisions.
Orderable Turn Around Time
10 Days
Orderable Biomarkers
NY Approved
False
Orderable Biomarkers JSON
{"DNA Sequencing": {"SNVs + Indels": ["CEBPA", "FLT3", "IDH1", "IDH2", "NPM1", "TP53"]}, "Fluorescence In Situ Hybridization (FISH)": {"Translocation(s)": ["PML/RARA t(15;17)", "RUNX1T1/RUNX1 (ETO/AML1) t(8;21)"], "Deletion(s)": ["17p-", "5q-", "7q-"], "Rearrangement(s)": ["MLL"], "CNVs": ["CBFB"]}}
Keywords string
AML, acute myeloid leukemia, risk stratification, client-bill Rapid AML Therapeutic Panel
Title URL
rapid-aml-therapeutic-panel
Clinical Significance
The Rapid AML Therapeutic Panel identifies genetic abnormalities associated with Acute Myeloid Leukemia (AML) that are useful for risk stratification and therapeutic decision making. This panel utilizes a combination of bi-directional Sanger sequencing, PCR and FISH with a fast turnaround time. AML is usually an in-patient hematologic diagnosis and prompt time to treatment assignment can improve patient outcomes significantly.
TAT Details
FISH: 5 Days
FLT3, IDH1, IDH2: 5 Days
CEBPA, NPM1, TP53: 7-10 Days
Storage and transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. For fresh samples: refrigerate before shipping and ship same day as drawn whenever possible. Do not freeze. Please select extract & hold - DNA if specimen hold service is desired.