Code
FSH-PMLR-01BX
Test
Active-Compendium
Automated Analysis: 88374x1.
Manual Analysis: Codes may differ.
Manual Analysis: Codes may differ.
Clinical
Pathology
<p>Bone Marrow Aspirate: 1-2 mL in sodium heparin tube. EDTA tube is acceptable.<br/>
Peripheral Blood: 2-5 mL in sodium heparin tube. EDTA tube is acceptable.<br/>
Fresh, Unfixed Tissue: Tissue in RPMI.<br/>
Bone Marrow/Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides: Minimum 1 slides, labeled with specimen type.<br/>
Fluids: Mix in equal parts with RPMI (specimen volume to RPMI ratio of 1:1).<br/>
Fixed Cell Suspension: A client-prepared fixed cell suspension is acceptable if received in 3:1 Methanol:Glacial Acetic Acid.</p>
Peripheral Blood: 2-5 mL in sodium heparin tube. EDTA tube is acceptable.<br/>
Fresh, Unfixed Tissue: Tissue in RPMI.<br/>
Bone Marrow/Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides: Minimum 1 slides, labeled with specimen type.<br/>
Fluids: Mix in equal parts with RPMI (specimen volume to RPMI ratio of 1:1).<br/>
Fixed Cell Suspension: A client-prepared fixed cell suspension is acceptable if received in 3:1 Methanol:Glacial Acetic Acid.</p>
Flag Active
True
Orderable Test Description
<p>This test uses PML/RARA t(15;17) probes to detect gene rearrangements associated with acute myeloid leukemia (AML) and acute promyelocytic leukemia (APL). <br><br>
Test Customization: STAT processing is available when ordered as a stand-alone test. Note MD contact name and phone number to receive STAT results.</p>
Test Customization: STAT processing is available when ordered as a stand-alone test. Note MD contact name and phone number to receive STAT results.</p>
Orderable Turn Around Time
4 Days
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"Fluorescence In Situ Hybridization (FISH)": {"Translocation(s)": ["PML/RARA t(15;17)"]}}
Keywords string
pml, rara, 15, 17 PML/RARA t(15;17)
Title URL
pml-rara-t15-17
Clinical Significance
PML/RARA translocations are commonly seen in acute promyelocytic leukemia (APL) in more than 90% of cases. Available separately or as part of the AML Standard FISH Panel and AML Favorable-Risk Panel.
TAT Details
STAT (upon request):
12-24 hours from receipt in the NeoGenomics laboratory
Storage and transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. For fresh samples: refrigerate before shipping and ship same day as drawn whenever possible. Do not freeze. NYS clients please provide date and time of collection.