Code
FSH-ETAM-01BX
Test
Active-Compendium
Automated Analysis: 88374x1.
Manual Analysis: Codes may differ.
Manual Analysis: Codes may differ.
Clinical
Pathology
<p>Bone Marrow Aspirate: 1-2 mL in sodium heparin tube. EDTA tube is acceptable.<br/>
Peripheral Blood: 2-5 mL in sodium heparin tube. EDTA tube is acceptable.<br/>
Fresh, Unfixed Tissue: Tissue in RPMI.<br/>
Bone Marrow/Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides: Minimum 1 slides, labeled with specimen type.<br/>
Fluids: Mix in equal parts with RPMI (specimen volume to RPMI ratio of 1:1).<br/>
Fixed Cell Suspension: A client-prepared fixed cell suspension is acceptable if received in 3:1 Methanol:Glacial Acetic Acid.</p>
Peripheral Blood: 2-5 mL in sodium heparin tube. EDTA tube is acceptable.<br/>
Fresh, Unfixed Tissue: Tissue in RPMI.<br/>
Bone Marrow/Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides: Minimum 1 slides, labeled with specimen type.<br/>
Fluids: Mix in equal parts with RPMI (specimen volume to RPMI ratio of 1:1).<br/>
Fixed Cell Suspension: A client-prepared fixed cell suspension is acceptable if received in 3:1 Methanol:Glacial Acetic Acid.</p>
Flag Active
True
Orderable Test Description
This test uses RUNX1T1/RUNX1 (ETO/AML1) t(8;21) probes to detect gene rearrangements associated with acute myeloid leukemia (AML-M2).
Orderable Turn Around Time
3-5 Days
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"Fluorescence In Situ Hybridization (FISH)": {"Translocation(s)": ["RUNX1T1/RUNX1 (ETO/AML1) t(8;21)"]}}
Keywords string
RUNX1, RUNX1T1, RUNX1, RUNX1T1 RUNX1, eto, AML1 RUNX1T1/RUNX1 (ETO/AML1) t(8;21)
Title URL
runx1t1-runx1-eto-aml1-t8-21
Clinical Significance
RUNX1T1/RUNX1 translocations play a critical role in the initiation and maintenance of AML. Available separately or as part of the AML Standard FISH Panel and AML Favorable-Risk Panel.
Storage and transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. For fresh samples: refrigerate before shipping and ship same day as drawn whenever possible. Do not freeze. NYS clients please provide date and time of collection.