Code
FSH-APMA-01BX
Test
Active-Compendium
Automated Analysis: 88374x1.
Manual Analysis: Codes may differ.
Manual Analysis: Codes may differ.
Clinical
Pathology
<p>Bone Marrow Aspirate: 1-2 mL in sodium heparin tube. EDTA tube is acceptable.<br/>
Peripheral Blood: 2-5 mL in sodium heparin tube. EDTA tube is acceptable.<br/>
Fresh, Unfixed Tissue: Tissue in RPMI.<br/>
Bone Marrow/Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides: Minimum 1 slides, labeled with specimen type.<br/>
Fluids: Mix in equal parts with RPMI (specimen volume to RPMI ratio of 1:1).<br/>
Fixed Cell Suspension: A client-prepared fixed cell suspension is acceptable if received in 3:1 Methanol:Glacial Acetic Acid.<br/>
H&E slide (required) plus paraffin block.<br/>
Cut Slides: H&E slide (required) plus 3 unstained slides cut at 4-5 microns.<br/>
Note for Tech Only clients: Please circle H&E slide.</p>
Peripheral Blood: 2-5 mL in sodium heparin tube. EDTA tube is acceptable.<br/>
Fresh, Unfixed Tissue: Tissue in RPMI.<br/>
Bone Marrow/Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides: Minimum 1 slides, labeled with specimen type.<br/>
Fluids: Mix in equal parts with RPMI (specimen volume to RPMI ratio of 1:1).<br/>
Fixed Cell Suspension: A client-prepared fixed cell suspension is acceptable if received in 3:1 Methanol:Glacial Acetic Acid.<br/>
H&E slide (required) plus paraffin block.<br/>
Cut Slides: H&E slide (required) plus 3 unstained slides cut at 4-5 microns.<br/>
Note for Tech Only clients: Please circle H&E slide.</p>
Flag Active
True
Orderable Test Description
This test uses BIRC3(API2)/MALT1 t(11;18) probes to detect gene rearrangements associated with MALT lymphoma and non-Hodgkin lymphoma (NHL).
Orderable Turn Around Time
3-5 Days
Keywords
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"Fluorescence In Situ Hybridization (FISH)": {"Translocation(s)": ["BIRC3(API2)/MALT1 t(11;18)"]}}
Keywords string
MALT lymphoma BIRC3(API2)/MALT1 t(11;18)
Title URL
birc3api2-malt1-t11-18
Clinical Significance
The BIRC3(API2)/MALT1 translocation is most common in B cell lymphomas, specifically marginal zone lymphomas (MZLs) of mucosa-associated lymphoid tissue (MALT).
Storage and transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. For fresh samples: refrigerate before shipping and ship same day as drawn whenever possible. Do not freeze. NYS clients please provide date and time of collection.